Guanine

Modify Date: 2025-08-21 11:31:27

Guanine structure	Common Name	Guanine
	CAS Number	73-40-5	Molecular Weight	151.126
	Density	2.2±0.1 g/cm3	Boiling Point	561.5±42.0 °C at 760 mmHg
	Molecular Formula	C₅H₅N₅O	Melting Point	>300 °C(lit.)
	MSDS	Chinese USA	Flash Point	293.4±27.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of Guanine

Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

Name	Guanine
Synonym	More Synonyms

Description	Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Cancer

Density	2.2±0.1 g/cm3
Boiling Point	561.5±42.0 °C at 760 mmHg
Melting Point	>300 °C(lit.)
Molecular Formula	C₅H₅N₅O
Molecular Weight	151.126
Flash Point	293.4±27.9 °C
Exact Mass	151.049408
PSA	100.45000
LogP	-2.03
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	2.047
Storage condition	2-8°C
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	practically insoluble

Guanine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MF8260000

CHEMICAL NAME :: Guanine

CAS REGISTRY NUMBER :: 73-40-5

LAST UPDATED :: 199709

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C5-H5-N5-O

MOLECULAR WEIGHT :: 151.15

WISWESSER LINE NOTATION :: T56 BM DN FVM INJ HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3333 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1300 mg/kg/26W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - ovarian tumors

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 15 mg/kg

REFERENCE :: NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 19,40,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2576 No. of Facilities: 1778 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 4133 (estimated) No. of Female Employees: 3339 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MF8260000

Precursor 9
CAS#:59277-89-3 Acyclovir CAS#:1874-58-4 9H-Purin-2-amin... CAS#:2387-48-6 2,6-diamino-5-n... CAS#:7440-06-4 platinum
CAS#:3056-33-5 N,9-Diacetylguanine CAS#:118-00-3 Guanosine CAS#:3641-10-9 2H-1,2,4-triazo... CAS#:961-07-9 2'-Deoxyguanosine
CAS#:1904-98-9 2,6-Diaminopurine
DownStream 10
CAS#:108436-36-8 2'-Monodehydrox... CAS#:39809-25-1 Penciclovir CAS#:3066-84-0 8-bromoguanine CAS#:506-77-4 Cyanogen chloride
CAS#:149948-29-8 N'-(6-chloro-7H... CAS#:39639-47-9 N-BENZYL-2-CHLO... CAS#:19188-42-2 Benzoic acid,4-... CAS#:214201-64-6 9-(2-Bromoethyl...
CAS#:59277-89-3 Acyclovir CAS#:127302-85-6 9-[[2-chloroeth...

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J. Bacteriol. 197(5) , 819-32, (2015)

Clostridium difficile is an anaerobic Gram-positive bacterium that causes intestinal infections with symptoms ranging from mild diarrhea to fulminant colitis. Cyclic diguanosine monophosphate (c-di-GM...

Electrochemical tuning of oxygen-containing groups on graphene oxides: towards control of the performance for the analysis of biomarkers.

Phys. Chem. Chem. Phys. 16(24) , 12178-82, (2014)

Graphene materials are very popular in the field of biosensing owing to their distinctive characteristics. However, oxygen-containing groups are known to exist intrinsically in graphene-related materi...

Development of an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) aptasensor for direct detection of DNA hybridization.

Phys. Chem. Chem. Phys. 17 , 21356-63, (2015)

Rapid detection of disease biomarkers at the patient point-of-care is essential to timely and effective treatment. The research described herein focuses on the development of an electrochemical surfac...

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Guanine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Guanine
Price: ￥98.0/50mg ￥168.0/100g ￥568.0/500g
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Guanine
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Huangshi Healthday Pharmaceutical Technology Co., Ltd.
China
Product Name: Guanine
Price: ￥Inquiry/25kg ￥Inquiry/100kg ￥Inquiry/1ton ￥Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Li
Email: sales@healthdaychem.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Guanine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Guanine

Use of Guanine

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Guanine Biological Activity

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Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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Precursor & DownStream

Articles218

Synonyms

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