Tos-PEG6-CH2CO2tBu

Modify Date: 2024-01-13 18:12:21

Tos-PEG6-CH2CO2tBu Structure
Tos-PEG6-CH2CO2tBu structure
Common Name Tos-PEG6-CH2CO2tBu
CAS Number 1949793-62-7 Molecular Weight 506.61
Density N/A Boiling Point N/A
Molecular Formula C23H38O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG6-CH2CO2tBu


Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tos-PEG5-CH2COOtBu
Synonym More Synonyms

 Tos-PEG6-CH2CO2tBu Biological Activity

Description Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H38O10S
Molecular Weight 506.61

 Synonyms

MFCD30828689
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