42749-28-0
42749-28-0 structure
- Name: Tos-PEG6-OH
- Chemical Name: 17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl 4-methylbenzenesulfonate
- CAS Number: 42749-28-0
- Molecular Formula: C19H32O9S
- Molecular Weight: 436.517
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-06 17:34:30
- Modify Date: 2024-01-22 19:35:28
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Tos-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl 4-methylbenzenesulfonate |
|---|---|
| Synonyms |
3,6,9,12,15-Pentaoxaheptadecane-1,17-diol, mono(4-methylbenzenesulfonate)
17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl 4-methylbenzenesulfonate |
| Description | Tos-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 555.5±50.0 °C at 760 mmHg |
| Molecular Formula | C19H32O9S |
| Molecular Weight | 436.517 |
| Flash Point | 289.7±30.1 °C |
| Exact Mass | 436.176697 |
| LogP | -0.84 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.503 |