Tos-PEG6-OH

Modify Date: 2024-01-22 19:35:28

Tos-PEG6-OH Structure
Tos-PEG6-OH structure
Common Name Tos-PEG6-OH
CAS Number 42749-28-0 Molecular Weight 436.517
Density 1.2±0.1 g/cm3 Boiling Point 555.5±50.0 °C at 760 mmHg
Molecular Formula C19H32O9S Melting Point N/A
MSDS N/A Flash Point 289.7±30.1 °C

 Use of Tos-PEG6-OH


Tos-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl 4-methylbenzenesulfonate
Synonym More Synonyms

 Tos-PEG6-OH Biological Activity

Description Tos-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 555.5±50.0 °C at 760 mmHg
Molecular Formula C19H32O9S
Molecular Weight 436.517
Flash Point 289.7±30.1 °C
Exact Mass 436.176697
LogP -0.84
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.503

 Synonyms

3,6,9,12,15-Pentaoxaheptadecane-1,17-diol, mono(4-methylbenzenesulfonate)
17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl 4-methylbenzenesulfonate
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: PEG7-Tos
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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