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406213-75-0

406213-75-0 structure
406213-75-0 structure
  • Name: Tos-PEG6-C2-Boc
  • Chemical Name: Tos-PEG7-t-butyl ester
  • CAS Number: 406213-75-0
  • Molecular Formula: C26H44O11S
  • Molecular Weight: 564.686
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-30 14:01:15
  • Modify Date: 2024-01-10 18:49:02
  • Tos-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Tos-PEG7-t-butyl ester
Synonyms 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
MFCD20926384
2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Description Tos-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Density 1.1±0.1 g/cm3
Boiling Point 621.1±55.0 °C at 760 mmHg
Molecular Formula C26H44O11S
Molecular Weight 564.686
Flash Point 329.4±31.5 °C
Exact Mass 564.260437
LogP 1.01
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.489
Storage condition 2-8℃
Hazard Codes Xn