850090-10-7
850090-10-7 structure
- Name: Tos-PEG5-C2-Boc
- Chemical Name: 2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15-pentaoxaoctadecan-18-oate
- CAS Number: 850090-10-7
- Molecular Formula: C24H40O10S
- Molecular Weight: 520.633
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-18 00:42:01
- Modify Date: 2024-01-02 16:54:17
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Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15-pentaoxaoctadecan-18-oate |
|---|---|
| Synonyms |
MFCD22683305
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester 2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15-pentaoxaoctadecan-18-oate |
| Description | Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 591.4±50.0 °C at 760 mmHg |
| Molecular Formula | C24H40O10S |
| Molecular Weight | 520.633 |
| Flash Point | 311.4±30.1 °C |
| Exact Mass | 520.234192 |
| LogP | 1.37 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.491 |
| Hazard Codes | Xi |
|---|