DHODH-IN-4

Modify Date: 2024-01-10 11:34:07

DHODH-IN-4 structure	Common Name	DHODH-IN-4
	CAS Number	1148125-93-2	Molecular Weight	347.20
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₂Cl₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DHODH-IN-4

DHODH-IN-4 (compound 17) is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor, with IC50 values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively. DHODH-IN-4 (compound 17) possess antimalarial activity[1].

Name	DHODH-IN-4

Description	DHODH-IN-4 (compound 17) is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor, with IC50 values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively. DHODH-IN-4 (compound 17) possess antimalarial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase Research Areas >> Inflammation/Immunology
Target	IC50: 4 μM (PfDHODH), 0.18 μM (HsDHODH)[1].
References	[1]. Davies M, et al. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93.

Molecular Formula	C₁₇H₁₂Cl₂N₂O₂
Molecular Weight	347.20

DC Chemicals Limited
China
Product Name: DHODH-IN-4
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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