16344-26-6

16344-26-6 structure

Name: DHODH-IN-17
Chemical Name: 2-(4-chloroanilino)pyridine-3-carboxylic acid
CAS Number: 16344-26-6
Molecular Formula: C₁₂H₉ClN₂O₂
Molecular Weight: 248.67
Catalog: Research Areas Cancer
Create Date: 2018-11-30 17:14:14
Modify Date: 2025-09-22 07:28:26
DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML)[1].

Name	2-(4-chloroanilino)pyridine-3-carboxylic acid
Synonyms	2-[(4-chlorophenyl)amino]-3-pyridinecarboxylic acid HMS2655G09 2-(4-chloro-anilino)-nicotinic acid 2-(4-Chloro-phenylamino)-nicotinic acid 2-(p-Chloranilino)-nicotinsaeure 2-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid

Description	DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML)[1].
Related Catalog	Research Areas >> Cancer
Target	IC50: 0.4 μM (DHODH)[1]
In Vitro	DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor with an IC50 value of 0.40 μM[1].
References	[1]. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117.

Molecular Formula	C₁₂H₉ClN₂O₂
Molecular Weight	248.67
Exact Mass	248.03500
PSA	62.22000
LogP	3.24980

918907-41-2

~99%

16344-26-6

Literature: Kamal, Ahmed; Srikanth; Naseer Ahmed Khan; Ashraf, Md.; Kashi Reddy; Sultana, Farheen; Kaur, Tandeep; Chashoo, Gousia; Suri, Nitasha; Sehar, Irum; Wani, Zahoor A.; Saxena, Arpita; Sharma, Parduman R.; Bhushan, Shashi; Mondhe, Dilip M.; Saxena, Ajit K. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 23 p. 7136 - 7150

2942-59-8

106-47-8

~92%

16344-26-6

Literature: Li, Zhenghua; Xiao, Shangyou; Liang, Ronghui; Xia, Zhining Research on Chemical Intermediates, 2012 , vol. 38, # 7 p. 1691 - 1697

106-47-8

16344-26-6

Literature: Kamal, Ahmed; Srikanth, Yellamelli Valli Venkata; Khan, Mohammed Naseer Ahmed; Ashraf, Mohammed; Sehar, Irum; Chashoo, Gousia; Sharma, Parduman Raj; Dar, Abid Hamid; Shashi, Bhushan; Singh, Shashank Kumar; Mondhe, Dilip Manikrao; Saxena, Ajit Kumar Patent: US2013/324734 A1, 2013 ;

1452-94-4

16344-26-6

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

16344-26-6	2511248-11-4
2450341-39-4	1263303-93-0
2450341-75-8	2685799-97-5
1148126-03-7	2639835-02-0
2742675-85-8	1263303-95-2
1373609-12-1	1701585-93-4
1695333-47-1	1689873-55-9
1289132-70-2	1690918-27-4
1694525-01-3	1697496-73-3
1697743-38-6	1698093-57-0