DHODH-IN-20

Modify Date: 2025-08-27 17:47:01

DHODH-IN-20 Structure
DHODH-IN-20 structure
Common Name DHODH-IN-20
CAS Number 2639835-02-0 Molecular Weight 479.47
Density N/A Boiling Point N/A
Molecular Formula C24H25F4N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DHODH-IN-20


DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia[1].

 Names

Name DHODH-IN-20

 DHODH-IN-20 Biological Activity

Description DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia[1].
Related Catalog
References

[1]. Sabnis RW. Biaryl Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia (AML). ACS Med Chem Lett. 2022;13(2):158-159.

 Chemical & Physical Properties

Molecular Formula C24H25F4N3O3
Molecular Weight 479.47
InChIKey JGGJFEOIKVIQJV-AWEZNQCLSA-N
SMILES Cc1ccccc1NC(=O)c1cc(F)c(-c2cn(C)c(C(C)(C)O)n2)cc1OC(C)C(F)(F)F
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