2639835-02-0

2639835-02-0 structure

Name: DHODH-IN-20
Chemical Name: DHODH-IN-20
CAS Number: 2639835-02-0
Molecular Formula: C₂₄H₂₅F₄N₃O₃
Molecular Weight: 479.47
Create Date: 2022-05-22 10:58:36
Modify Date: 2025-08-27 17:47:01
DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia[1].

Name	DHODH-IN-20

Description	DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Inflammation/Immunology
References	[1]. Sabnis RW. Biaryl Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia (AML). ACS Med Chem Lett. 2022;13(2):158-159.

Molecular Formula	C₂₄H₂₅F₄N₃O₃
Molecular Weight	479.47