HIV-1 inhibitor-55
Modify Date: 2025-08-30 07:00:49
HIV-1 inhibitor-55 structure
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Common Name | HIV-1 inhibitor-55 | ||
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| CAS Number | 2771211-73-3 | Molecular Weight | 548.66 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H32N6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HIV-1 inhibitor-55HIV-1 inhibitor-55 (compound 4d) inhibits WT HIV-1 with an EC50 value of 8.6 nM. HIV-1 inhibitor-55 also shows inhibitory potency against single and double HIV-1 mutants. HIV-1 inhibitor-55 can be used for the research of virus infection[1]. |
| Name | HIV-1 inhibitor-55 |
|---|
| Description | HIV-1 inhibitor-55 (compound 4d) inhibits WT HIV-1 with an EC50 value of 8.6 nM. HIV-1 inhibitor-55 also shows inhibitory potency against single and double HIV-1 mutants. HIV-1 inhibitor-55 can be used for the research of virus infection[1]. |
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| Related Catalog | |
| In Vitro | HIV-1 inhibitor-55 对野生型 HIV-1 表现出抑制作用，EC50 值为 8.6 nM[1]。 HIV-1 inhibitor-55 对 HIV-1 突变体 L100I，K103N，Y181C，Y188L，E138K 和 F227L + V106A 表现出较强的抗逆转录酶活性，其 EC50 值分别为 1.1、0.12、0.36、0.75、0.033 和 3.06 μM[1]。 HIV-1 inhibitor-55 抑制野生型 HIV-1 逆转录的活性，IC50 值为 0.11 μM[1]。 |
| References |
| Molecular Formula | C28H32N6O4S |
|---|---|
| Molecular Weight | 548.66 |
| InChIKey | PYASWAJWQIJRIM-UHFFFAOYSA-N |
| SMILES | Cc1cc(C)c(Oc2ccnc(NC3CCN(C(=O)c4cc5cc(NS(C)(=O)=O)ccc5[nH]4)CC3)n2)c(C)c1 |