NAD+

Modify Date: 2025-08-22 11:53:25

NAD+ structure	Common Name	NAD+
	CAS Number	53-84-9	Molecular Weight	663.425
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₇N₇O₁₄P₂	Melting Point	140 - 142ºC
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS08	Signal Word	Warning

Use of NAD+

NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

Name	NAD zwitterion
Synonym	More Synonyms

Description	NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
Related Catalog	Research Areas >> Metabolic Disease Natural Products >> Saccharides and Glycosides
Target	Human Endogenous Metabolite
In Vitro	NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ is the oxidized form of NADH[1]. NAD+ is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) [2].
In Vivo	Oral NAD+ supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia[3].
References	[1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70. [2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92. [3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12.

Melting Point	140 - 142ºC
Molecular Formula	C₂₁H₂₇N₇O₁₄P₂
Molecular Weight	663.425
Exact Mass	663.109131
PSA	340.71000
LogP	-5.72
InChIKey	BAWFJGJZGIEFAR-NNYOXOHSSA-O
SMILES	NC(=O)c1ccc[n+](C2OC(COP(=O)(O)OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)C(O)C2O)c1

NAD+ MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU3450000

CHEMICAL NAME :: Pyridinium, 3-carbamoyl-1-beta-D-ribofuranosyl-, hydroxide, 5'-ester with adenosine 5'- 5'-(trihydrogen pyrophosphate), inner salt

CAS REGISTRY NUMBER :: 53-84-9

BEILSTEIN REFERENCE NO. :: 3584133

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H27-N7-O14-P2

MOLECULAR WEIGHT :: 663.49

WISWESSER LINE NOTATION :: T56 BN DN GN INJ FZ B- BT5OJ CQ DQ E1OPWOPWO1- BT5OTJ CQ DQ E- AT6KJ CVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4333 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 45,327,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3384 No. of Facilities: 499 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 4168 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3384 No. of Facilities: 1731 (estimated) No. of Industries: 5 No. of Occupations: 13 No. of Employees: 26664 (estimated) No. of Female Employees: 19782 (estimated)

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H371
Precautionary Statements	P260
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn,F,Xi
Risk Phrases	R36
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UU3450000
HS Code	29349990

Precursor 9
CAS#:58-68-4 NADH CAS#:1094-61-7 β-Nicotinamide ... CAS#:24558-92-7 ADENOSINE 5'-MO... CAS#:18784-01-5 N1-(2,3,5-Tri-O...
CAS#:78687-39-5 N1-(β-D-Ribofur... CAS#:78687-38-4 3-carbamoyl-1-(... CAS#:6450-77-7 1-[5-[[[[5-(6-A... CAS#:61-19-8 5'-Adenylic acid
CAS#:56-65-5 Adenosine triph...
DownStream 8
CAS#:36791-04-5 Ribavirin CAS#:22596-06-1 1H-Benzotriazol... CAS#:98-92-0 Nicotinamide CAS#:20762-30-5 [5-(6-aminopuri...
CAS#:61-19-8 5'-Adenylic acid CAS#:73-24-5 Adenine CAS#:58-64-0 Adenosine dipho... CAS#:119340-53-3 Cyclic ADP-ribose

HS Code	29349990

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b-Diphosphopyridine Nucleotide

DPN

beta-Diphosphopyrid

MFCD00036253

Coenzyme I Hydrate,oxidized form

Diphosphopyridine nucleotide

Cozymase Hydrate,oxidized form

β-Nicotinamide adenine dinucleotide

EINECS 200-184-4

β-Diphosphopyridine Nucleotide Hydrate,oxidized form

β-NAD Hydrate,oxidized form

Adenine-D-ribose-phosphate-phosphate-D-ribose-nicotinamide

b-Nicotinamide Adenine Dinucleotide

β-DPN Hydrate,oxidized form

Adenosine 5'-(Trihydrogen Diphosphate) P'®5'-ester with 3-(Aminocarbonyl)-1-b-D-ribofuranosylpyridinium hydroxide Inner Salt

Codehydrogenase

β-Nicotinamide Adenine Dinucleotide Hydrate,oxidized form

3-Carbamoyl-1-b-D-ribofuranosylpyridinium hydroxide 5'®5'-ester with Adenosine 5'-(Trihydrogen Pyrophosphate) Inner Salt

ARPPRN

b-NAD

Cozymase

beta-Diphosphopyridine nucleotide

β-NAD

β-Nicotinamide adenine dinucleotide hydrate

NAD

β-DPN

NAD+

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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: NAD+
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Price: $66/10mM*1mLinWater

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NAD+

Use of NAD+

Names

NAD+ Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Precursor & DownStream

Customs

Articles286

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.