5'-Adenylic acid

Modify Date: 2024-01-01 22:13:07

5'-Adenylic acid Structure
5'-Adenylic acid structure
Common Name 5'-Adenylic acid
CAS Number 61-19-8 Molecular Weight 347.221
Density 2.3±0.1 g/cm3 Boiling Point 798.5±70.0 °C at 760 mmHg
Molecular Formula C10H14N5O7P Melting Point 178-185 °C
MSDS N/A Flash Point 436.7±35.7 °C

 Use of 5'-Adenylic acid


Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

 Names

Name amp
Synonym More Synonyms

 5'-Adenylic acid Biological Activity

Description Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Adenosine monophosphate is a product of various enzymatic reactions, many of which are dysregulated during disease conditions[1].
References

[1]. Mondal S, et al. Utility of Adenosine Monophosphate Detection System for Monitoring the Activities of Diverse Enzyme Reactions. Assay Drug Dev Technol. 2017 Oct/Nov;15(7):330-341.

 Chemical & Physical Properties

Density 2.3±0.1 g/cm3
Boiling Point 798.5±70.0 °C at 760 mmHg
Melting Point 178-185 °C
Molecular Formula C10H14N5O7P
Molecular Weight 347.221
Flash Point 436.7±35.7 °C
Exact Mass 347.063080
PSA 195.88000
LogP -0.22
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.905
Water Solubility H2O: with addition of mild alkalisoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7480500
CHEMICAL NAME :
5'-Adenylic acid
CAS REGISTRY NUMBER :
61-19-8
BEILSTEIN REFERENCE NO. :
0054612
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C10-H14-N5-O7-P
MOLECULAR WEIGHT :
347.26
WISWESSER LINE NOTATION :
T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQQO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
2800 mg/kg
SEX/DURATION :
female 7-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
2800 mg/kg
SEX/DURATION :
female 7-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - mouse Cells - not otherwise specified
DOSE/DURATION :
50 umol/L
REFERENCE :
JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 66,313,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3805 No. of Facilities: 973 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 12179 (estimated) No. of Female Employees: 8315 (estimated)

 Safety Information

Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AU7480500
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

a-5mp
5'-AMP
phosphate d'adénosine
adenovite
ADENOSINE-5'-MONOPHOSPHORIC ACID
[(2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl dihydrogen phosphate
EINECS 200-500-0
Adenosine-5'-monophosphate
myoston
MFCD00005750
t-Adenylic Acid
adenosine phosphate
5'-Adenylic acid
phosphate d'adenosine
phosaden
AMP
adenosine-5′-monophosphate
adenyl
Ado-5'-P
adenosine 5′-monophosphate
my-b-den
Adenosine-5'-phosphoric Acid
Adenosine 5'-monophosphate
Adenosine 5'-phosphoric acid
lycedan
Adenosine monophosphate
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