53-84-9

53-84-9 structure

Name: NAD+
Chemical Name: NAD zwitterion
CAS Number: 53-84-9
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.425
Catalog: API Vitamins and minerals Vitamin B drugs
Create Date: 2018-04-08 08:00:00
Modify Date: 2025-08-22 11:53:25
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

Name	NAD zwitterion
Synonyms	b-Diphosphopyridine Nucleotide DPN beta-Diphosphopyrid MFCD00036253 Coenzyme I Hydrate,oxidized form Diphosphopyridine nucleotide Cozymase Hydrate,oxidized form β-Nicotinamide adenine dinucleotide EINECS 200-184-4 β-Diphosphopyridine Nucleotide Hydrate,oxidized form β-NAD Hydrate,oxidized form Adenine-D-ribose-phosphate-phosphate-D-ribose-nicotinamide b-Nicotinamide Adenine Dinucleotide β-DPN Hydrate,oxidized form Adenosine 5'-(Trihydrogen Diphosphate) P'®5'-ester with 3-(Aminocarbonyl)-1-b-D-ribofuranosylpyridinium hydroxide Inner Salt Codehydrogenase β-Nicotinamide Adenine Dinucleotide Hydrate,oxidized form 3-Carbamoyl-1-b-D-ribofuranosylpyridinium hydroxide 5'®5'-ester with Adenosine 5'-(Trihydrogen Pyrophosphate) Inner Salt ARPPRN b-NAD Cozymase beta-Diphosphopyridine nucleotide β-NAD β-Nicotinamide adenine dinucleotide hydrate NAD β-DPN NAD+

Description	NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
Related Catalog	Research Areas >> Metabolic Disease Natural Products >> Saccharides and Glycosides
Target	Human Endogenous Metabolite
In Vitro	NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ is the oxidized form of NADH[1]. NAD+ is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) [2].
In Vivo	Oral NAD+ supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia[3].
References	[1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70. [2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92. [3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12.

CHEMICAL NAME :: Pyridinium, 3-carbamoyl-1-beta-D-ribofuranosyl-, hydroxide, 5'-ester with adenosine 5'- 5'-(trihydrogen pyrophosphate), inner salt

WISWESSER LINE NOTATION :: T56 BN DN GN INJ FZ B- BT5OJ CQ DQ E1OPWOPWO1- BT5OTJ CQ DQ E- AT6KJ CVZ

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 45,327,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3384 No. of Facilities: 499 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 4168 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3384 No. of Facilities: 1731 (estimated) No. of Industries: 5 No. of Occupations: 13 No. of Employees: 26664 (estimated) No. of Female Employees: 19782 (estimated)

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H371
Precautionary Statements	P260
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn,F,Xi
Risk Phrases	R36
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UU3450000
HS Code	29349990