Scutellarein

Modify Date: 2025-08-22 19:54:53

Scutellarein Structure
Scutellarein structure
Common Name Scutellarein
CAS Number 529-53-3 Molecular Weight 286.236
Density 1.7±0.1 g/cm3 Boiling Point 642.9±55.0 °C at 760 mmHg
Molecular Formula C15H10O6 Melting Point 330ºC
MSDS Chinese USA Flash Point 249.9±25.0 °C

 Use of Scutellarein


Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases.

 Names

Name Scutellarein
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 642.9±55.0 °C at 760 mmHg
Melting Point 330ºC
Molecular Formula C15H10O6
Molecular Weight 286.236
Flash Point 249.9±25.0 °C
Exact Mass 286.047729
PSA 111.13000
LogP 2.54
Appearance of Characters yellow
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.768
InChIKey JVXZRQGOGOXCEC-UHFFFAOYSA-N
SMILES O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12
Storage condition 2-8°C
Water Solubility DMSO: soluble1mg/mL, clear, greenish-yellow

 Safety Information

Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 2914501900

 Synthetic Route

 Customs

HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles29

More Articles
Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C.

Biol. Pharm. Bull. 39 , 181-91, (2016)

Erigeron breviscapus has been widely used in traditional Chinese medicine (TCM) and its total flavonoid component is commonly used to treat ischemic stroke, coronary heart disease, diabetes and hypert...

Liquid Chromatography-Tandem Mass Spectrometry Screening Method for the Detection of Radical-Scavenging Natural Antioxidants from the Whole Scutellariae (Radix, Stem and Leaf).

J. Chromatogr. Sci. 53 , 1140-6, (2015)

A novel free radical reaction combined with high-performance LC-photodiode array-ESI-MS/MS screening method was developed for the detection and identification of natural antioxidants from whole Scutel...

Effect of light, methyl jasmonate and cyclodextrin on production of polyphenolic compounds in hairy root cultures of Scutellaria lateriflora

Phytochemistry 107 , 50-60, (2014)

Graphical abstract [Display omitted]

 ScutellareinBioassay

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Name: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of O...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 2B1
External Id: CHEMBL5260630
Name: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of O...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 2B1
External Id: CHEMBL5260629
Name: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of O...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 2B1
External Id: CHEMBL5260631
Name: Solubility of compound in water at 0.1 to 10 ug/ml by UV spectrophotometry relative t...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3636113
Name: Antioxidant activity assessed as DDPH radical scavenging activity
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1225535
Name: Solubility of compound in water at 0.1 to 10 ug/ml by UV spectrophotometry
Source: ChEMBL
Target: N/A
External Id: CHEMBL3636112
Name: Inhibition of HCV NS3 helicase overexpressed in Escherichia coli BL21(DE3) assessed a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060535
Name: Binding affinity towards benzodiazepine site in GABAA receptor
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit theta
External Id: CHEMBL877825
Name: Inhibition of SARS coronavirus nsP13 ATP hydrolysis activity expressed in Escherichia...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060536
Name: Inhibition of cow milk xanthine oxidase
Source: ChEMBL
Target: Xanthine dehydrogenase/oxidase
External Id: CHEMBL1015631
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 Synonyms

5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
5,6,7,4'-tetrahydroxyflavone
5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4',5,6,7-Tetrahydroxyflavanone
6-Hydroxypelargidenon 1465
Scutellarein
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