1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane
![1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane Structure](https://image.chemsrc.com/caspic/319/470-67-7.png)
1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane structure
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Common Name | 1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane | ||
|---|---|---|---|---|
| CAS Number | 470-67-7 | Molecular Weight | 154.249 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 173.5±8.0 °C at 760 mmHg | |
| Molecular Formula | C10H18O | Melting Point | −46 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 50.7±15.3 °C | |
| Symbol |
GHS02 |
Signal Word | Warning | |
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Inhibition by menthol and its related chemicals of compound action potentials in frog sciatic nerves.
Life Sci. 92(6-7) , 359-67, (2013) Transient receptor potential (TRP) vanilloid-1 (TRPV1) and melastatin-8 (TRPM8) channels play a role in transmitting sensory information in primary-afferent neurons. TRPV1 agonists at high concentrations inhibit action potential conduction in the neurons and ... |
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1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1.
Mol. Pain 8 , 86, (2012) Essential oils are often used in alternative medicine as analgesic and anti-inflammatory remedies. However, the specific compounds that confer the effects of essential oils and the molecular mechanisms are largely unknown. TRPM8 is a thermosensitive receptor ... |
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[Analysis of the chemical constituents of essential oil from Chimonanthus zhejiangensis by GC-MS].
Zhong Yao Cai 33(3) , 385-7, (2010) To analyze the chemical constituents of the essential oil from Chimonanthus zhejiangensis.Steam distillation was employed to extract volatile compounds of essential oil from Chimonanthus zhejiangensis. Volatile compounds of essential oil were isolated and ide... |
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[GC-MS analysis of constituents of essential oils from stems of Ephedra sinica Stapf, E. intermedia Schrenk et C.A. Mey. and E. equisetina Bge].
Zhongguo Zhong Yao Za Zhi 22(8) , 489-92, 512, (1997) The essential oils from the dried stems of Ephedra sinica, E. intermedia and E. equisetina were analyzed by GC-MS qualitatively and GC quantitatively. One hundred and twenty-seven constituents were identified, l-alpha-terpineol (31.64%) in E. sinica, 1,4-cine... |
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A soluble Bacillus cereus cytochrome P-450cin system catalyzes 1,4-cineole hydroxylations.
Appl. Environ. Microbiol. 59(11) , 3889-93, (1993) A cytochrome P-450-dependent monooxygenase system that catalyzes the stereospecific hydroxylation of the monoterpene substrate 1,4-cineole was demonstrated in cell-free preparations of Bacillus cereus UI-1477. 1,4-Cineole hydroxylations were catalyzed by a 10... |
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Anxiolytic-like effect of the monoterpene 1,4-cineole in mice.
Pharmacol. Biochem. Behav. 96(3) , 287-93, (2010) Recent studies have shown that some monoterpenes exert anxiolytic- and depressant-like actions, however, these effects from monoterpene 1,4-cineole are still unknown. This work aimed to study the effects of 1,4-cineole in classic animal models for depression-... |
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Roles of cytochrome P450 3A enzymes in the 2-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes.
Xenobiotica 31(10) , 713-23, (2001) 1. Oxidation of 1,4-cineole, a monoterpene cyclic ether, was studied in rat and human liver microsomes and recombinant cytochrome P450 (P450 or CYP) enzymes expressed in insect cells in which human P450 and NADPH-P450 reductase cDNAs have been introduced. On ... |
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Toxicity of Rhododendron anthopogonoides essential oil and its constituent compounds towards Sitophilus zeamais.
Molecules 16(9) , 7320-30, (2011) The screening of several Chinese medicinal plants for insecticidal principles showed that essential oil of Rhododendron anthopogonoides flowering aerial parts possessed significant toxicity against maize weevils, Sitophilus zeamais. A total of 37 components w... |
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Interactions between novel terpenes and main components of rat and human skin: mechanistic view for transdermal delivery of propranolol hydrochloride.
Curr. Drug Deliv. 8(2) , 213-24, (2011) The purpose of this study was to investigate the effectiveness and mechanism(s) of percutaneous absorption of propranolol hydrochloride (PHCL) across rat and human cadaver skin using seven novel terpenes with reference to marker terpene 1,8-cineole. In-vitro ... |
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Biotransformation of 1,4-cineole, a monoterpene ether.
Xenobiotica 18(10) , 1129-34, (1988) 1. The metabolism of 1,4-cineole, a monoterpene ether, was studied in the rabbit. 2. Four neutral and one acidic metabolites were isolated from the urine and shown to be 9-hydroxy-1,4-cineole, 3,8-dihydroxy-1,4-cineole, 8,9-dihydroxy-1,4-cineole, 1,4-cineole-... |