Xenobiotica 1988-10-01

Biotransformation of 1,4-cineole, a monoterpene ether.

Y Asakawa, M Toyota, T Ishida

Index: Xenobiotica 18(10) , 1129-34, (1988)

Full Text: HTML

Abstract

1. The metabolism of 1,4-cineole, a monoterpene ether, was studied in the rabbit. 2. Four neutral and one acidic metabolites were isolated from the urine and shown to be 9-hydroxy-1,4-cineole, 3,8-dihydroxy-1,4-cineole, 8,9-dihydroxy-1,4-cineole, 1,4-cineole-8-en-9-ol and 1,4-cineole-9-carboxylic acid.