Phenazepam
Phenazepam structure
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Common Name | Phenazepam | ||
|---|---|---|---|---|
| CAS Number | 51753-57-2 | Molecular Weight | 349.610 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 493.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C15H8BrClN2O | Melting Point | 225-230ºC | |
| MSDS | Chinese USA | Flash Point | 251.9±28.7 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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[Distribution of 14C-phenazepam and its metabolites in the liver, brain and blood plasma in single and prolonged administration to white rats].
Farmakol. Toksikol. 43(2) , 144-8, (1980) The distribution pattern of 14C-phenazepam and some of its metabolites in the liver, brain and blood plasma at a prolonged (45 days) administration to rats does not differ from that after a single administration. The liver and brain demonstrated an increase i... |
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Phenazepam and its effects on driving.
J. Anal. Toxicol. 37(1) , 25-9, (2013) Phenazepam use in the state of Georgia has increasingly become a trend for a drug market looking at new and different recreational drugs. This paper examines the psychomotor effects of phenazepam on individuals and their ability to operate a motor vehicle. Th... |
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First reported case in the UK of acute prolonged neuropsychiatric toxicity associated with analytically confirmed recreational use of phenazepam.
Eur. J. Clin. Pharmacol. 69(3) , 361-3, (2013) There is increasing evidence from around Europe of the availability and misuse of long-acting benzodiazepines such as phenazepam. There is little information on the acute toxicity of these compounds; we describe here a case of analytically confirmed phenazepa... |
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Phenazepam: the drug that came in from the cold.
J. Forensic Leg. Med. 19(3) , 122-5, (2012) In the past few years there has been concern in Western Europe and in the US about the rise in abuse of phenazepam, a benzodiazepine that was originally developed in the USSR in the mid- to late 1970s.(1-4) Although phenazepam is one of the most widely prescr... |
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Phenazepam abuse in the UK: an emerging problem causing serious adverse health problems, including death.
Hum. Psychopharmacol. Clin. Exp. 27(3) , 254-61, (2012) Phenazepam (fenazepam; 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; PNZ, 'Bonsai') is a benzodiazepine developed in the former Soviet Union during the 1970s to treat neurological disorders, epilepsy, and alcohol withdrawal syndrome. Its ... |
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Reactivity of commercial benzodiazepine immunoassays to phenazepam.
J. Anal. Toxicol. 36(3) , 207-9, (2012) Phenazepam is a long acting benzodiazepine that is not controlled in Canada, the United States or many European countries. The abuse of phenazepam has gained recent attention due to the number of hospitalizations and fatalities resulting from overdose. The co... |
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Effects of physicochemical forms of phenazepam and Panavir on their action at ultra-low doses.
Bull. Exp. Biol. Med. 153(4) , 455-8, (2012) A concept of physicochemical forms of biologically active substances introduced in investigation of the action mechanism of ultra-low doses allows qualitative explanation of the main effects of ultra-low doses, chemical diversity of biologically active substa... |
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Study of bipathic effect of phenazepam.
Bull. Exp. Biol. Med. 144 , 536-538, (2007) Phenazepam in ultralow doses significantly potentiated anxiolytic and anticonvulsant effects of therapeutic doses of the same drug both after preliminary or simultaneous administration, which attests to bipathic action of phenazepam. The combination of ultral... |
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Anxiolytic and antidepressant effects of aqueous tincture of the aerial part of Myosotis arvensis.
Bull. Exp. Biol. Med. 151(5) , 604-6, (2011) Experiments on outbred albino mice showed a significant anxiolytic effect of aqueous tincture of the aerial part of Myosotis arvensis (L.) (Boraginaceae) in a single daily dose of 0.5 ml/kg. In a dose of 2 ml/kg, the tincture of M. arvensis aerial part exhibi... |
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The use of tenoten and tenoten (pediatric formulation) as a drug for premedication in adults and children during outpatients dentist visit.
Bull. Exp. Biol. Med. 148(2) , 340-2, (2009) The use of tenoten and tenoten (pediatric formulation) for premedication in adults and children before dental treatment reduces patient anxiety; the effect is comparable with that of classical anxiolytics and is not accompanied by side effects. These preparat... |