Bulletin of Experimental Biology and Medicine 2007-10-01

Study of bipathic effect of phenazepam.

O I Epstein, T A Voronina, G M Molodavkin, M V Belopol'skaya, I A Kheyfets, J L Dugina, S A Sergeeva

Index: Bull. Exp. Biol. Med. 144 , 536-538, (2007)

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Abstract

Phenazepam in ultralow doses significantly potentiated anxiolytic and anticonvulsant effects of therapeutic doses of the same drug both after preliminary or simultaneous administration, which attests to bipathic action of phenazepam. The combination of ultralow and therapeutic doses of phenazepam prevented the development of its specific myorelaxant and sedative side effects.