Bulletin of Experimental Biology and Medicine 2011-09-01

Anxiolytic and antidepressant effects of aqueous tincture of the aerial part of Myosotis arvensis.

N Yu Polomeyeva, R V Gurto, O S Bryushinina, V A Slepichev, A V Kaigorodtsev, V Yu Smirnov, N I Suslov, V V Udut

Index: Bull. Exp. Biol. Med. 151(5) , 604-6, (2011)

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Abstract

Experiments on outbred albino mice showed a significant anxiolytic effect of aqueous tincture of the aerial part of Myosotis arvensis (L.) (Boraginaceae) in a single daily dose of 0.5 ml/kg. In a dose of 2 ml/kg, the tincture of M. arvensis aerial part exhibited an anxiolytic and antidepressant effect. In contrast to phenazepam, aqueous tincture of M. arvensis did not inhibit exploratory and motor activities.