Trypsin
Trypsin structure
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Common Name | Trypsin | ||
|---|---|---|---|---|
| CAS Number | 9002-07-7 | Molecular Weight | 372.1 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H15O12P3 | Melting Point | 115°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.
Nature Chemistry 6(10) , 885-92, (2014) Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity ... |
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The effect of amniotic membrane de-epithelialization method on its biological properties and ability to promote limbal epithelial cell culture.
Invest. Ophthalmol. Vis. Sci. 54(4) , 3072-81, (2013) We characterized the de-epithelialized human amniotic membrane (HAM), and compared cell attachment and proliferation efficiencies.HAM was de-epithelialized by 20% ethanol (AHAM), 1.2 U/mL Dispase (DHAM), 0.02% EDTA (EHAM), 0.25% trypsin-EDTA (THAM), and 5 M u... |
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Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner.
PLoS Pathog. 7(8) , e1002188, (2011) Rabbit Hemorrhagic disease virus (RHDV), a calicivirus of the Lagovirus genus, and responsible for rabbit hemorrhagic disease (RHD), kills rabbits between 48 to 72 hours post infection with mortality rates as high as 50-90%. Caliciviruses, including norovirus... |
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Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury.
Basic Res. Cardiol. 110 , 53, (2015) Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that contributes a crucial role in protection against ischemia (ISC)-reperfusion (REP) injury by driving expression of anti-apoptotic and anti-oxidant genes. STAT3 is also pr... |
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Suppression of astrovirus replication by an ERK1/2 inhibitor.
J. Virol. 82(15) , 7475-82, (2008) Human astroviruses are nonenveloped, positive-sense single-strand RNA viruses associated with self-limiting diarrhea. Although they are recognized as a leading cause of disease in young children, the cellular factors involved in astrovirus replication are not... |
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Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph disease.
Hum. Mol. Genet. 23(18) , 4932-44, (2014) Machado-Joseph Disease (MJD) is the most prevalent autosomal dominantly inherited cerebellar ataxia. It is caused by an expanded CAG repeat in the ATXN3 gene, which translates into a polyglutamine tract within the ataxin-3 protein. Present treatments are symp... |
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AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells.
Exp. Eye Res. 132 , 136-50, (2015) The ionotropic glutamate receptors (iGLuR) have been hypothesized to play a role in neuronal pathogenesis by mediating excitotoxic death. Previous studies on iGluR in the retina have focused on two broad classes of receptors: NMDA and non-NMDA receptors inclu... |
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Oxidative stress, neurotoxicity, and non-specific immune responses in juvenile red sea bream, Pagrus major, exposed to different waterborne selenium concentrations.
Chemosphere 135 , 46-52, (2015) Juvenile Pagrus major (mean length 15.8±1.6 cm, and mean weight 90.4±4.7 g) were exposed for 4 weeks with waterborne selenium concentration (0, 50, 100, 200, and 400 μg L(-1)). In oxidative stress indicators, liver and gill superoxide dismutase (SOD) activity... |
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Discrimination of in vitro and in vivo digestion products of meat proteins from pork, beef, chicken, and fish.
Proteomics 15 , 3688-98, (2015) In vitro digestion products of proteins were compared among beef, pork, chicken, and fish. Gastric and jejunal contents from the rats fed these meat proteins were also compared. Cooked pork, beef, chicken, and fish were homogenized and incubated with pepsin a... |
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Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro.
J. Neuroinflammation 12 , 71, (2015) Neuro-inflammation has long been implicated as a contributor to the progression of Alzheimer's disease in both humans and animal models. Type-1 interferons (IFNs) are pleiotropic cytokines critical in mediating the innate immune pro-inflammatory response. The... |