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胱胺二盐酸盐

胱胺二盐酸盐结构式
胱胺二盐酸盐结构式
品牌特惠专场
常用名 胱胺二盐酸盐 英文名 Cystamine dihydrochloride
CAS号 56-17-7 分子量 225.203
密度 1.172g/cm3 沸点 264.8ºC at 760mmHg
分子式 C4H14Cl2N2S2 熔点 217-220 °C (dec.)(lit.)
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Curcumin delivery from poly(acrylic acid-co-methyl methacrylate) hollow microparticles prevents dopamine-induced toxicity in rat brain synaptosomes.

Int. J. Pharm. 486 , 259-67, (2015)

The potential of poly(methyl methacrylate-co-acrylic acid) (PMMA-AA) copolymers to form hollow particles and their further formulation as curcumin delivery system have been explored. The particles were functionalized by crosslinking the acrylic acid groups vi...

ROP and ATRP Fabricated Dual Targeted Redox Sensitive Polymersomes Based on pPEGMA-PCL-ss-PCL-pPEGMA Triblock Copolymers for Breast Cancer Therapeutics.

ACS Appl. Mater. Interfaces 7 , 9211-27, (2015)

To minimize cardiotoxicity and to increase the bioavailability of doxorubicin, polymersomes based on redox sensitive amphiphilic triblock copolymer poly(polyethylene glycol methacrylate)-poly(caprolactone)-s-s-poly(caprolactone)-poly(polyethylene glycol metha...

Glycopolymer micelles with reducible ionic cores for hepatocytes-targeting delivery of DOX.

Int. J. Pharm. 441(1-2) , 170-80, (2013)

A novel galactose-decorated cross-linked micelles (cl-micelles) with ionic cores using cystamine (Cys) as a biodegradable cross-linker was prepared by using block ionomer complexes of poly(ethylene glycol)-b-poly(2-acryloxyethyl-galactose)-b-poly(acrylic acid...

Gold nanoparticles immobilized hydrophilic monoliths with variable functional modification for highly selective enrichment and on-line deglycosylation of glycopeptides.

Anal. Chim. Acta 900 , 83-9, (2015)

The poly (glycidyl methacrylate-co-poly (ethylene glycol) diacrylate) monoliths modified with gold nanoparticles, with advantages of enhanced reactive sites, good hydrophilicity and facile modification, were prepared as the matrix, followed by variable functi...

Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase.

Mol. Cell. 50(6) , 882-93, (2013)

Transcriptional pausing, which regulates transcript elongation in both prokaryotes and eukaryotes, is thought to involve formation of alternative RNA polymerase conformations in which nucleotide addition is inhibited in part by restriction of trigger loop (TL...

Selective Capture and Quick Detection of Targeting Cells with SERS-Coding Microsphere Suspension Chip.

Small 11 , 2200-8, (2015)

Circulating tumor cells (CTCs) captured from blood fluid represent recurrent cancers and metastatic lesions to monitor the situation of cancers. We develop surface-enhanced Raman scattering (SERS)-coding microsphere suspension chip as a new strategy for fast ...

A novel serum metabolomics-based diagnostic approach for colorectal cancer.

PLoS ONE 7(7) , e40459, (2012)

To improve the quality of life of colorectal cancer patients, it is important to establish new screening methods for early diagnosis of colorectal cancer.We performed serum metabolome analysis using gas-chromatography/mass-spectrometry (GC/MS). First, the acc...

Hepatocellular carcinoma dually-targeted nanoparticles for reduction triggered intracellular delivery of doxorubicin.

Int. J. Pharm. 478(2) , 553-68, (2015)

Hepatocellular carcinoma (HCC) dual targeted stimuli responsive nanoparticles (NPs) for intracellular delivery of doxorubicin (DOX) were developed based on a reduction cleavable hyaluronic acid-glycyrrhetinic acid conjugate (HA-Cyst-GA). HA-Cyst-GA conjugate ...

Volume change of double cross-linked poly(aspartic acid) hydrogels induced by cleavage of one of the crosslinks.

Acta Biomater. 9(2) , 5122-31, (2013)

In the present paper we report for the first time the development of redox-responsive biocompatible polymer gels. Double cross-linked poly(aspartic acid) hydrogels were prepared using two different cross-linking agents simultaneously. One of the cross-linkers...

Functional properties and biodistribution of poly(triethylenetetramine/cystamine bisacrylamide) and poly(triethylenetetramine/cystamine bisacrylamide)- poly(ethylene glycol) mixtures formed with nucleic acid.

J. Control. Release 159(1) , 111-9, (2012)

The clinical success of non-viral gene delivery reagents is hampered by their inefficient cellular transgene delivery, which is largely influenced by carrier properties that are currently undefined and misunderstood. In an attempt to further define and unders...