7-Aminocephalosporanic acid

Modify Date: 2025-08-21 12:12:09

7-Aminocephalosporanic acid Structure
7-Aminocephalosporanic acid structure
Common Name 7-Aminocephalosporanic acid
CAS Number 957-68-6 Molecular Weight 272.278
Density 1.6±0.1 g/cm3 Boiling Point 560.6±50.0 °C at 760 mmHg
Molecular Formula C10H12N2O5S Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 292.9±30.1 °C
Symbol GHS08
GHS08
Signal Word Danger

 Use of 7-Aminocephalosporanic acid


7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics, is a potent β-lactamase inhibitor.

 Names

Name 7β-aminocephalosporanic acid
Synonym More Synonyms

 7-Aminocephalosporanic acid Biological Activity

Description 7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics, is a potent β-lactamase inhibitor.
Related Catalog

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 560.6±50.0 °C at 760 mmHg
Melting Point >300 °C(lit.)
Molecular Formula C10H12N2O5S
Molecular Weight 272.278
Flash Point 292.9±30.1 °C
Exact Mass 272.046692
PSA 135.23000
LogP -0.80
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.661
Storage condition 2-8°C

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H317-H334
Precautionary Statements P261-P280-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn,Xi
Risk Phrases R42/43:May cause sensitization by inhalation and skin contact . R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Phrases S22-S36/37-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934996000

 Synthetic Route

~80%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1804 - 1810

~94%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Fernandez-Lafuente, Roberto; Guisan, Jose M.; Pregnolato, Massimo; Terreni, Marco Tetrahedron Letters, 1997 , vol. 38, # 26 p. 4693 - 4696

~%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1804 - 1810

~%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1804 - 1810

~%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Advanced Synthesis and Catalysis, , vol. 350, # 2 p. 343 - 348

~%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Advanced Synthesis and Catalysis, , vol. 345, # 6-7 p. 783 - 789

~84%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Kametani; Sekine; Honda Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 12 p. 4545 - 4547

~%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Advanced Synthesis and Catalysis, , vol. 350, # 2 p. 343 - 348

~%

7-Aminocephalosporanic acid Structure

7-Aminocephalos...

CAS#:957-68-6

Literature: Journal of Molecular Catalysis B: Enzymatic, , vol. 76, p. 52 - 58

 Customs

HS Code 2934996000
Summary 2934996000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:6.0%. General tariff:20.0%

 Articles28

More Articles
Construction of recombinant Escherichia coli D11/pMSTO and its use in enzymatic preparation of 7-aminocephalosporanic acid in one pot.

J. Biotechnol. 129(3) , 400-5, (2007)

The main drawback in the industrial production of 7-aminocephalosporanic acid is the accumulation of intermediate (AKA-7-ACA) and destruction of substrate (cephalosporin C) catalyzed by catalase and b...

Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase.

Appl. Microbiol. Biotechnol. 65(3) , 263-7, (2004)

Bacillus subtilis SHS0133 cephalosporin-C deacetylase (CAH) overexpressed in Escherichia coli was immobilized on an anion-exchange resin, KA-890, using glutaraldehyde. The activity yield of immobilize...

Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules.

Eur. J. Pharm. Sci. 32(1) , 1-7, (2007)

Acid-base chemistry of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporanic acid (7-ACA), the fundamental units of the two classical antibiotic families is characterised at the macroscopic and ...

 Synonyms

7-ACS
(7R)-7-Aminocephalosporanic acid
EINECS 213-485-0
7-AMINO CEPHALOSPORIC ACID
(6R,7R)-3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)-
7beta-aminocephalosporanic acid
7β-aminocephalosporanic acid zwitterion
3-Acetoxymethyl-7-aminoceph-3-em-4-oic Acid
7β-aminocephalosporanic acid
7-Amino
MFCD00005177
7-Aminocephalosporanicacid
7-Aminocephalsporanic acid
7-Aminocephalosporanic acid
7-ACA
(6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Acetate Ester
Cefazolin Impurity 1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here







Get all suppliers and price by the below link:

7-Aminocephalosporanic acid suppliers


Price: ¥78/5g

Reference only. check more 7-Aminocephalosporanic acid price

Related Compounds: More...
glutaryl-7-aminocephalosporanic acid
27920-90-7
7-aminocephalosporanic acid methyl ester
27285-70-7
7-Aminocephalosporanic acid t-butyl ester
6187-87-7
Hydroxymethyl-7-Aminocephalosporanic acid
15690-38-7
3-deacetyloxy-7-aminocephalosporanic acid
26395-99-3
3-deacetyloxy-7-aminocephalosporanic acid
72059-35-9
3-methoxymethyl-7-aminocephalosporanic acid
24701-69-7
N-(2-oxoadipoyl)-7-aminocephalosporanic acid
28242-83-3
desacetyl glutaryl 7-aminocephalosporanic acid
55779-10-7
(2E)-2-[(5-methoxy-1-methyl-1H-indol-3-yl)methylidene]-7-methyl-3-oxo-2,3-dihydro-1-benzofuran-6-yl 2-methylbenzoate
929418-23-5
4-(3,4-Dimethoxyphenyl)-11,12-dimethyl-10-(pyridin-2-ylmethyl)-3,5,6,8,10-pentazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaene
929966-38-1
(Z)-8-(pyridin-3-ylmethyl)-2-(thiophen-2-ylmethylene)-8,9-dihydro-2H-benzofuro[7,6-e][1,3]oxazin-3(7H)-one
929967-50-0
C17H15ClFN3O4
1013753-38-2
2-methoxy-N-{(5Z)-5-[(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)methylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}benzamide
929968-06-9
(Z)-2-((2-(2-ethoxybenzylidene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetonitrile
623120-25-2
3-(2-methoxyphenyl)-9-(2-morpholinoethyl)-9,10-dihydrochromeno[8,7-e][1,3]oxazin-4(8H)-one
929444-57-5
(Z)-2-(3-bromobenzylidene)-8-(pyridin-2-ylmethyl)-8,9-dihydro-2H-benzofuro[7,6-e][1,3]oxazin-3(7H)-one
929962-03-8
3-[(4S)-1-[2-(5-fluoro-1H-indol-3-yl)ethyl]-2,5-dioxoimidazolidin-4-yl]-N-prop-2-enylpropanamide
1013753-96-2
2-[(1-Ethylindol-3-yl)methylene]-3-oxobenzo[3,4-b]furan-6-yl methylsulfonate
929417-88-9