t-Boc-N-amido-PEG5-acetic acid

Modify Date: 2024-01-21 11:16:21

t-Boc-N-amido-PEG5-acetic acid structure	Common Name	t-Boc-N-amido-PEG5-acetic acid
	CAS Number	890152-41-7	Molecular Weight	395.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₃₃NO₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of t-Boc-N-amido-PEG5-acetic acid

BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	BocNH-PEG5-acid
Synonym	More Synonyms

Description	BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula	C₁₇H₃₃NO₉
Molecular Weight	395.45

2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid, Boc-NH-PEG5-CH2COOH

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