t-Boc-N-amido-PEG5-NHS ester

Modify Date: 2024-01-16 21:08:44

t-Boc-N-amido-PEG5-NHS ester Structure
t-Boc-N-amido-PEG5-NHS ester structure
Common Name t-Boc-N-amido-PEG5-NHS ester
CAS Number 2055040-78-1 Molecular Weight 506.54
Density N/A Boiling Point N/A
Molecular Formula C22H38N2O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-N-amido-PEG5-NHS ester


Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Boc-N-PEG5-C2-NHS ester
Synonym More Synonyms

 t-Boc-N-amido-PEG5-NHS ester Biological Activity

Description Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C22H38N2O11
Molecular Weight 506.54
Storage condition 2-8°C

 Synonyms

MFCD29764335