Quinolinic acid

Modify Date: 2025-08-20 19:00:57

Quinolinic acid structure	Common Name	Quinolinic acid
	CAS Number	89-00-9	Molecular Weight	167.119
	Density	1.6±0.1 g/cm3	Boiling Point	425.0±30.0 °C at 760 mmHg
	Molecular Formula	C₇H₅NO₄	Melting Point	188-190ºC
	MSDS	Chinese USA	Flash Point	210.9±24.6 °C
	Symbol	GHS07	Signal Word	Warning

Use of Quinolinic acid

Quinolinic acid is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction.

Name	quinolinic acid
Synonym	More Synonyms

Description	Quinolinic acid is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
References	[1]. Heyes MP, et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain. 1992 Oct;115 ( Pt 5):1249-73.

Density	1.6±0.1 g/cm3
Boiling Point	425.0±30.0 °C at 760 mmHg
Melting Point	188-190ºC
Molecular Formula	C₇H₅NO₄
Molecular Weight	167.119
Flash Point	210.9±24.6 °C
Exact Mass	167.021851
PSA	87.49000
LogP	-1.44
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.628
InChIKey	GJAWHXHKYYXBSV-UHFFFAOYSA-N
SMILES	O=C(O)c1cccnc1C(=O)O
Storage condition	Store at RT
Water Solubility	0.55 g/100 mL

Quinolinic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7967250

CHEMICAL NAME :: 2,3-Pyridinedicarboxylic acid

CAS REGISTRY NUMBER :: 89-00-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H5-N-O4

MOLECULAR WEIGHT :: 167.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 1050 mg/kg

SEX/DURATION :: female 1-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

REFERENCE :: ETPAEK Experimental and Toxicologic Pathology. (Gustav Fischer Verlag Jena, Postfach 100537, D-07705 Jena, Germany) V.44- 1992- Volume(issue)/page/year: 46,323,1994

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319-H335
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	US7967250
HS Code	29333999

Precursor 10
CAS#:91-22-5 leucoline CAS#:98-98-6 2-Picolinic acid CAS#:124-38-9 Carbon dioxide CAS#:2050-22-8 Diethyl pyridin...
CAS#:18704-37-5 8-Quinolinesulf... CAS#:148-24-3 8-Hydroxyquinoline CAS#:548-93-6 3-Hydroxyanthra... CAS#:91-63-4 Quinaldine
CAS#:91-62-3 6-Methylquinoline CAS#:611-32-5 8-Methylquinoline
DownStream 10
CAS#:4430-77-7 Pyrido[2,3-d]py... CAS#:36052-27-4 Methyl 3-aminop... CAS#:321-02-8 Nicotinic acid ... CAS#:4664-00-0 3,4-Pyridinedic...
CAS#:498-95-3 Nipecotic acid CAS#:82949-15-3 cis-2,3-piperid... CAS#:4043-87-2 Pipecolic acid CAS#:18970-62-2 2,3-Pyridinedic...
CAS#:59-67-6 Nicotinic acid CAS#:98-92-0 Nicotinamide

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

The CB₁ cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway.

Cell Death Differ. 22 , 1618-29, (2015)

The CB1 cannabinoid receptor, the main molecular target of endocannabinoids and cannabis active components, is the most abundant G protein-coupled receptor in the mammalian brain. In particular, the C...

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.

J. Neuroinflammation 12 , 110, (2015)

During inflammation, the kynurenine pathway (KP) metabolises the essential amino acid tryptophan (TRP) potentially contributing to excitotoxicity via the release of quinolinic acid (QUIN) and 3-hydrox...

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

2,3-Pyridinedicarboxylic acid

MFCD00006295

EINECS 201-874-8

Quinolinic acid

UNII-F6F0HK1URN

T6NJ BVQ CVQ

Pyridine-2,3-dicarboxylic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Quinolinic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Quinolinic acid
Price: ￥218.0/100g ￥78.0/25g
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Quinolinic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: quinolinic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Quinolinic acid
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

Get all suppliers and price by the below link:

Quinolinic acid suppliers

Price: ￥33/10g

Reference only. check more Quinolinic acid price

Quinolinic acid

Use of Quinolinic acid

Names

Quinolinic acid Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles110

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.