79055-67-7

79055-67-7 structure
79055-67-7 structure
  • Name: L-AP5
  • Chemical Name: l-ap5
  • CAS Number: 79055-67-7
  • Molecular Formula: C5H12NO5P
  • Molecular Weight: 197.13
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
  • Create Date: 2017-01-18 17:32:18
  • Modify Date: 2024-01-02 20:25:48
  • L-AP5 (L-APV; L-2-Amino-5-phosphonovaleric acid) is an NMDA antagonist and is the isomer of D-AP5 (HY-100714A).L-AP5 shows a relatively weak amino acid and synaptic blocking activity[1].

Name l-ap5
Synonyms D(-)-APV
L-AP5
[3H]-D(-)-2-Amino-5-phosphonopentanoic acid
D-2-Amino-5-phosphonovaleric acid
D-2-Amino-5-phosphopentanoic acid
L-Norvaline, 5-phosphono-
5-Phosphono-D-norvaline
D-Norvaline,5-phosphono
L-(+)-2-Amino-5-phosphonopentanoic acid
Quinolinic acid
D-AP5
D(-)-2-Amino-5-phosphonopentanoic acid
Description L-AP5 (L-APV; L-2-Amino-5-phosphonovaleric acid) is an NMDA antagonist and is the isomer of D-AP5 (HY-100714A).L-AP5 shows a relatively weak amino acid and synaptic blocking activity[1].
Related Catalog
Target

NMDA Receptor

References

[1]. Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378  

Density 1.5±0.1 g/cm3
Boiling Point 482.1±55.0 °C at 760 mmHg
Molecular Formula C5H12NO5P
Molecular Weight 197.13
Flash Point 245.4±31.5 °C
Exact Mass 197.045303
PSA 130.66000
LogP -2.32
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.536
Name: L(+)-2-Amino-5-phosphonovaleric acid 95% (>99% e.e.) 0.25 mole EtOH Material Safety Data Sheet
Synonym: L-5-Phosphononorvaline; L-2-Amino-5-phosphonopentanoic acid; L-AP-5; 5-Phosphono-L-norvaline; L-2-Amino-5-phosphonopentanoic acid; L-2-Amino-5-phosphonovaleric acid
CAS: 79055-67-7
Section 1 - Chemical Product MSDS Name:L(+)-2-Amino-5-phosphonovaleric acid 95% (>99% e.e.) 0.25 mole EtOH Material Safety Data Sheet
Synonym:L-5-Phosphononorvaline; L-2-Amino-5-phosphonopentanoic acid; L-AP-5; 5-Phosphono-L-norvaline; L-2-Amino-5-phosphonopentanoic acid; L-2-Amino-5-phosphonovaleric acid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
79055-67-7 L-(+)-2-Amino-5-phosphonovaleric acid 95 unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Use water spray to keep fire-exposed containers cool.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid breathing dust.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 79055-67-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: white
Odor: No data
pH: Not available.
Vapor Pressure: Negligible
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 100 - 110 deg C
Autoignition Temperature: Not available.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C5H12NO5P
Molecular Weight: 197.13

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Strong oxidizers.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of phosphorus, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 79055-67-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
L-(+)-2-Amino-5-phosphonovaleric acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 79055-67-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 79055-67-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 79055-67-7 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36