11β-HSD1-IN-9

Modify Date: 2023-02-05 08:00:26

11β-HSD1-IN-9 Structure
11β-HSD1-IN-9 structure
Common Name 11β-HSD1-IN-9
CAS Number 88283-34-5 Molecular Weight 266.21900
Density 1.32g/cm3 Boiling Point 363ºC at 760 mmHg
Molecular Formula C13H9F3N2O Melting Point N/A
MSDS N/A Flash Point 173.3ºC

 Use of 11β-HSD1-IN-9


11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].

 Names

Name 2-pyrazin-2-yl-1-[4-(trifluoromethyl)phenyl]ethanone

 11β-HSD1-IN-9 Biological Activity

Description 11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].
Related Catalog

 Chemical & Physical Properties

Density 1.32g/cm3
Boiling Point 363ºC at 760 mmHg
Molecular Formula C13H9F3N2O
Molecular Weight 266.21900
Flash Point 173.3ºC
Exact Mass 266.06700
PSA 42.85000
LogP 2.92080
Index of Refraction 1.526

 Safety Information

Hazard Codes Xi: Irritant;
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%