859721-81-6
859721-81-6 structure
- Name: 11β-HSD1-IN-11
- Chemical Name: 11β-HSD1-IN-11
- CAS Number: 859721-81-6
- Molecular Formula: C15H11F3O3S
- Molecular Weight: 328.31
- Catalog: Research Areas Metabolic Disease
- Create Date: 2023-02-03 09:55:20
- Modify Date: 2024-04-05 19:03:55
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11β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1].
| Name | 11β-HSD1-IN-11 |
|---|
| Description | 11β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.13 μM (Rat 11β-HSD1), 0.34 μM (Human 11β-HSD1)[1] |
| In Vivo | A single dose of the 11β-HSD1 inhibitor Merck 544 reduced the overall abundance of 11β-HSD1-IN-11 (Compound c1a) (15 mg/kg; oral gavage; once) in the rat liver[1]. |
| Molecular Formula | C15H11F3O3S |
|---|---|
| Molecular Weight | 328.31 |