11β-HSD1-IN-11
Modify Date: 2025-10-16 19:34:15
11β-HSD1-IN-11 structure
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Common Name | 11β-HSD1-IN-11 | ||
|---|---|---|---|---|
| CAS Number | 859721-81-6 | Molecular Weight | 328.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H11F3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 11β-HSD1-IN-1111β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1]. |
| Name | 11β-HSD1-IN-11 |
|---|
| Description | 11β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.13 μM (Rat 11β-HSD1), 0.34 μM (Human 11β-HSD1)[1] |
| In Vivo | A single dose of the 11β-HSD1 inhibitor Merck 544 reduced the overall abundance of 11β-HSD1-IN-11 (Compound c1a) (15 mg/kg; oral gavage; once) in the rat liver[1]. |
| Molecular Formula | C15H11F3O3S |
|---|---|
| Molecular Weight | 328.31 |
| InChIKey | PDXUGNITDTZZFN-UHFFFAOYSA-N |
| SMILES | O=C(CS(=O)(=O)c1ccccc1)c1ccc(C(F)(F)F)cc1 |