11β-HSD1-IN-6

Modify Date: 2024-02-02 10:00:14

11β-HSD1-IN-6 Structure
11β-HSD1-IN-6 structure
Common Name 11β-HSD1-IN-6
CAS Number 1303515-33-4 Molecular Weight 378.85
Density N/A Boiling Point N/A
Molecular Formula C21H19ClN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 11β-HSD1-IN-6


11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively[1].

 Names

Name 11β-HSD1-IN-6

 11β-HSD1-IN-6 Biological Activity

Description 11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively[1].
Related Catalog
References

[1]. Bo Qu, et al. Large-Scale Enantioselective Reduction of 2,3-Disubstituted Indenopyridine Enables a Practical Manufacturing Process for an 11β-HSD-1 Inhibitor. Org. Process Res. Dev. 2022, 26(3):963–975.

 Chemical & Physical Properties

Molecular Formula C21H19ClN4O
Molecular Weight 378.85
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