1303515-33-4

1303515-33-4 structure

Name: 11β-HSD1-IN-6
Chemical Name: 11β-HSD1-IN-6
CAS Number: 1303515-33-4
Molecular Formula: C₂₁H₁₉ClN₄O
Molecular Weight: 378.85
Catalog: Research Areas Metabolic Disease
Create Date: 2022-05-28 18:21:29
Modify Date: 2024-02-02 10:00:14
11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively[1].

Name	11β-HSD1-IN-6

Description	11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Bo Qu, et al. Large-Scale Enantioselective Reduction of 2,3-Disubstituted Indenopyridine Enables a Practical Manufacturing Process for an 11β-HSD-1 Inhibitor. Org. Process Res. Dev. 2022, 26(3):963–975.

Molecular Formula	C₂₁H₁₉ClN₄O
Molecular Weight	378.85