MAO-B-IN-9 structure
|
Common Name | MAO-B-IN-9 | ||
|---|---|---|---|---|
| CAS Number | 2416910-88-6 | Molecular Weight | 300.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H24N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MAO-B-IN-9MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1]. |
| Name | MAO-B-IN-9 |
|---|
| Description | MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1]. |
|---|---|
| Related Catalog | |
| Target |
MAO-B:0.178 ± 0. μM (IC50) |
| References |
| Molecular Formula | C18H24N2O2 |
|---|---|
| Molecular Weight | 300.40 |
| InChIKey | LJYBWYFQBIECKG-UHFFFAOYSA-N |
| SMILES | C#CCN1CCC(OC(=O)Nc2ccc(C(C)C)cc2)CC1 |