MAO-B-IN-9

Modify Date: 2024-01-02 11:43:44

MAO-B-IN-9 Structure
MAO-B-IN-9 structure
Common Name MAO-B-IN-9
CAS Number 2416910-88-6 Molecular Weight 300.40
Density N/A Boiling Point N/A
Molecular Formula C18H24N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAO-B-IN-9


MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1].

 Names

Name MAO-B-IN-9

 MAO-B-IN-9 Biological Activity

Description MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1].
Related Catalog
Target

MAO-B:0.178 ± 0. μM (IC50)

References

[1]. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.

 Chemical & Physical Properties

Molecular Formula C18H24N2O2
Molecular Weight 300.40
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