MAO-B-IN-13

Modify Date: 2025-08-25 17:27:52

MAO-B-IN-13 Structure
MAO-B-IN-13 structure
Common Name MAO-B-IN-13
CAS Number 2105918-34-9 Molecular Weight 297.35
Density N/A Boiling Point N/A
Molecular Formula C18H19NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAO-B-IN-13


MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor with an IC50 value of 10 nM. MAO-B-IN-13 has neuroprotective and antioxidant activity. MAO-B-IN-13 can be used for researching Parkinson’s disease[1].

 Names

Name MAO-B-IN-13

 MAO-B-IN-13 Biological Activity

Description MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor with an IC50 value of 10 nM. MAO-B-IN-13 has neuroprotective and antioxidant activity. MAO-B-IN-13 can be used for researching Parkinson’s disease[1].
Related Catalog
Target

MAO-B:10 nM (IC50)

In Vitro MAO-B-IN-13 (compound 12a) (1 μM, 10 μM and 50 μM; 48 hours) has neuroprotective effect on H2O2-induced PC-12 cell injury[1].
References

[1]. Li W, et al. Pyridoxine-resveratrol hybrids as novel inhibitors of MAO-B with antioxidant and neuroprotective activities for the treatment of Parkinson's disease. Bioorg Chem. 2020 Apr;97:103707.

 Chemical & Physical Properties

Molecular Formula C18H19NO3
Molecular Weight 297.35
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