Dihydrofolic acid

Modify Date: 2025-08-21 18:19:20

Dihydrofolic acid Structure
Dihydrofolic acid structure
Common Name Dihydrofolic acid
CAS Number 4033-27-6 Molecular Weight 443.41300
Density 1.69g/cm3 Boiling Point N/A
Molecular Formula C19H21N7O6 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Dihydrofolic acid


Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid.

 Names

Name dihydrofolic acid
Synonym More Synonyms

 Dihydrofolic acid Biological Activity

Description Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.69g/cm3
Molecular Formula C19H21N7O6
Molecular Weight 443.41300
Exact Mass 443.15500
PSA 211.89000
LogP 0.62870
Index of Refraction 1.762
Storage condition -20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Synthetic Route

~82%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Khilifa; Ganguly; Bieri; Viscontini Helvetica Chimica Acta, 1980 , vol. 63, # 8 p. 2554 - 2558

~%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

Dihydrofolic acid Structure

Dihydrofolic acid

CAS#:4033-27-6

Literature: Shiota; Disraely Biochimica et Biophysica Acta, 1961 , vol. 52, p. 467,468 Full Text Show Details Shiota Archives of Biochemistry, 1959 , vol. 80, p. 155,156

~%

Detail
Literature: Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

 Articles34

More Articles
Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.

Mol. Pharm. 11(8) , 2631-9, (2014)

The antifolate drug methotrexate (MTX) can serve as a dual-functional ligand in antitumoral drug delivery, inducing both a folate receptor mediated cellular uptake and an intracellular cytotoxic actio...

A domino effect in antifolate drug action in Escherichia coli.

Nat. Chem. Biol. 4 , 602-8, (2008)

Mass spectrometry technologies for measurement of cellular metabolism are opening new avenues to explore drug activity. Trimethoprim is an antibiotic that inhibits bacterial dihydrofolate reductase (D...

Methotrexate-gelonin conjugate - an inhibitor of MCF-7 cells expressing the dihydrofolate receptor.

Biol. Chem. 395(12) , 1461-6, (2014)

An immunotoxin composed of gelonin, a basic ribosome-inactivating protein, type I of 30 kDa, isolated from the seeds of the Indian plant Gelonium multiflorum and methotrexate (MTX) has been studied as...

 Synonyms

7,8-Dihydropteroyl-L-glutamic acid Dihydropteroyl-L-glutamic acid
DIHYDROFOLIC ACID
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Dihydrofolic acid suppliers


Price: ¥1200/5 mg

Reference only. check more Dihydrofolic acid price