二氢叶酸

更新时间:2024-01-02 10:40:26

二氢叶酸结构式
二氢叶酸结构式
品牌特惠专场
常用名 二氢叶酸 英文名 Dihydrofolic acid
CAS号 4033-27-6 分子量 443.41300
密度 1.69g/cm3 沸点 N/A
分子式 C19H21N7O6 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

 二氢叶酸用途


Dihydrofolic acid 是一种叶酸衍生物,由二氢叶酸还原酶作用转化为四氢叶酸。

 二氢叶酸名称

中文名 二氢叶酸
英文名 dihydrofolic acid
英文别名 更多

 二氢叶酸生物活性

描述 Dihydrofolic acid 是一种叶酸衍生物,由二氢叶酸还原酶作用转化为四氢叶酸。
相关类别
靶点

Human Endogenous Metabolite

 二氢叶酸物理化学性质

密度 1.69g/cm3
分子式 C19H21N7O6
分子量 443.41300
精确质量 443.15500
PSA 211.89000
LogP 0.62870
折射率 1.762
储存条件 -20°C

 二氢叶酸安全信息

符号 GHS07
GHS07
信号词 Warning
危害声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xi: Irritant;
风险声明 (欧洲) 36/37/38
安全声明 (欧洲) 26-36
危险品运输编码 NONH for all modes of transport

 二氢叶酸合成线路

~82%

二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Khilifa; Ganguly; Bieri; Viscontini Helvetica Chimica Acta, 1980 , vol. 63, # 8 p. 2554 - 2558

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二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

~%

二氢叶酸结构式

二氢叶酸

4033-27-6

文献:Shiota; Disraely Biochimica et Biophysica Acta, 1961 , vol. 52, p. 467,468 Full Text Show Details Shiota Archives of Biochemistry, 1959 , vol. 80, p. 155,156

~%

详细
文献:Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

 二氢叶酸文献34

更多文献
Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.

Mol. Pharm. 11(8) , 2631-9, (2014)

The antifolate drug methotrexate (MTX) can serve as a dual-functional ligand in antitumoral drug delivery, inducing both a folate receptor mediated cellular uptake and an intracellular cytotoxic actio...

A domino effect in antifolate drug action in Escherichia coli.

Nat. Chem. Biol. 4 , 602-8, (2008)

Mass spectrometry technologies for measurement of cellular metabolism are opening new avenues to explore drug activity. Trimethoprim is an antibiotic that inhibits bacterial dihydrofolate reductase (D...

Methotrexate-gelonin conjugate - an inhibitor of MCF-7 cells expressing the dihydrofolate receptor.

Biol. Chem. 395(12) , 1461-6, (2014)

An immunotoxin composed of gelonin, a basic ribosome-inactivating protein, type I of 30 kDa, isolated from the seeds of the Indian plant Gelonium multiflorum and methotrexate (MTX) has been studied as...

 二氢叶酸英文别名

7,8-Dihydropteroyl-L-glutamic acid Dihydropteroyl-L-glutamic acid
DIHYDROFOLIC ACID
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