28459-40-7

28459-40-7 structure

Name: 10-Formyl-7,8-dihydrofolic acid
Chemical Name: 10-formyldihydrofolic acid
CAS Number: 28459-40-7
Molecular Formula: C₂₀H₂₁N₇O₇
Molecular Weight: 471.42300
Catalog: Research Areas Metabolic Disease
Create Date: 2016-06-05 18:23:29
Modify Date: 2025-08-25 11:54:26
10-Formyl-7,8-dihydrofolic acid is a substrate for mammalian aminoimidazolecarboxamide ribotide transformylase (EC 2.1.2.3). 10-Formyl-7,8-dihydrofolic acid also is a metabolite of 10-HCO-H4folate[1][2].

Name	10-formyldihydrofolic acid
Synonyms	10-Formyl-7,8-dihydro Folic Acid (2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid

Description	10-Formyl-7,8-dihydrofolic acid is a substrate for mammalian aminoimidazolecarboxamide ribotide transformylase (EC 2.1.2.3). 10-Formyl-7,8-dihydrofolic acid also is a metabolite of 10-HCO-H4folate[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Baggott JE, et al. Iron compounds catalyze the oxidation of 10-formyl-5,6,7,8 tetrahydrofolic acid to 10-formyl-7,8 dihydrofolic acid. J Inorg Biochem. 1998 Sep;71(3-4):181-7. [2]. Baggott JE, et al. Metabolism of 10-formyldihydrofolate in humans. Biomed Pharmacother. 2001 Oct;55(8):454-7.

135-16-0

816-90-0

28459-40-7

Literature: Miller et al. Archives of Biochemistry, 1956 , vol. 63, p. 263

Precursor 2
135-16-0 816-90-0
DownStream 0