Folic Acid

Folic Acid Structure
Folic Acid
Share to Facebook Share to Twitter Share to Linkedin
Common Name Folic Acid
CAS Number 59-30-3 Molecular Weight 441.397
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C19H19N7O6 Melting Point 250 °C
MSDSFolic Acid MSDS|SDS|pdf download Chinese USA Flash Point N/A

 Names

[ Name ]: folic acid
[ Synonym ]: More Synonyms

 Chemical & Physical Properties

[ Density ]: 1.6±0.1 g/cm3
[ Melting Point ]: 250 °C
[ Molecular Formula ]: C19H19N7O6
[ Molecular Weight ]: 441.397
[ Exact Mass ]: 441.139679
[ PSA ]: 213.28000
[ LogP ]: -2.48
[ Index of Refraction ]: 1.755
[ Water Solubility ]: 1.6 mg/L (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LP5425000
CHEMICAL NAME :
Folic acid
CAS REGISTRY NUMBER :
59-30-3
LAST UPDATED :
199806
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C19-H19-N7-O6
MOLECULAR WEIGHT :
441.45
WISWESSER LINE NOTATION :
T66 BN DN GN JNJ CZ EQ H1MR DVMYVQ2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
85 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Behavioral - coma
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes Blood - changes in spleen
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
282 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
150 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)
TYPE OF TEST :
Unscheduled DNA synthesis
TYPE OF TEST :
Unscheduled DNA synthesis

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 29,136,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1051 No. of Facilities: 220 (estimated) No. of Industries: 4 No. of Occupations: 14 No. of Employees: 11106 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1051 No. of Facilities: 2823 (estimated) No. of Industries: 11 No. of Occupations: 40 No. of Employees: 60281 (estimated) No. of Female Employees: 29903 (estimated)

 Safety Information

[ Personal Protective Equipment ]: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]: Xn
[ Risk Phrases ]: R33;R62;R68
[ Safety Phrases ]: S24/25
[ RIDADR ]: NONH for all modes of transport
[ WGK Germany ]: 1
[ RTECS ]: LP5425000
[ HS Code ]: 2936290090

 Customs

[ HS Code ]: 2936290090

 Articles306

More Articles
Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging.

BMC Genomics 16 , 151, (2015)

Leishmania use exosomes to communicate with their mammalian hosts and these secreted vesicles appear to contribute to pathogenesis by delivering protein virulence factors to macrophages. In other euka...

Obesity is associated with increased red blood cell folate despite lower dietary intakes and serum concentrations.

J. Nutr. 145(1) , 79-86, (2015)

Folates are essential cofactors in metabolic pathways that facilitate biological methylation and nucleotide synthesis, and therefore have widespread effects on health and diseases. Although obesity is...

Graphene-oxide stabilization in electrolyte solutions using hydroxyethyl cellulose for drug delivery application.

Int. J. Pharm. 484(1-2) , 276-82, (2015)

Stabilization of graphene oxide (GO) in physiological solution is performed using hydroxyethyl cellulose (HEC) to make the resultant nanohybrid suitable for targeted drug delivery purposes. Short and ...

Top Suppliers:




  • MedChem Express
  • China
  • Product Name: Folic acid
  • Price: ¥960.0/10g ¥600.0/5g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Miss Gao

Get all suppliers and price by the below link:

Folic Acid suppliers


Price: $79/10mM*1mLinDMSO

Reference only. check more Folic Acid price