CYP3A4-IN-3

Modify Date: 2024-08-09 16:36:20

CYP3A4-IN-3 structure	Common Name	CYP3A4-IN-3
	CAS Number	2562384-19-2	Molecular Weight	569.76
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₃₉N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CYP3A4-IN-3

CYP3A4-IN-3 is a high-affinity specific inhibitor of cytochrome P450 3A4 (CYP3A4) with the IC50 value of 0.075 μM. CYP3A4-IN-3 is a ritonavir analogue, but with a simpler structure and twice the inhibitory effect of ritonavir. CYP3A4-IN-3 is used as an antiviral agent and immunosuppressant[1].

Name	CYP3A4-IN-3

Description	CYP3A4-IN-3 is a high-affinity specific inhibitor of cytochrome P450 3A4 (CYP3A4) with the IC50 value of 0.075 μM. CYP3A4-IN-3 is a ritonavir analogue, but with a simpler structure and twice the inhibitory effect of ritonavir. CYP3A4-IN-3 is used as an antiviral agent and immunosuppressant[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Inflammation/Immunology
Target	CYP3A4:0.075 μM (IC50)
References	[1]. Eric R Samuels, et al. An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4. Bioorg Med Chem. 2020 Mar 15;28(6):115349. doi: 10.1016/j.bmc.2020.115349. Epub 2020 Jan 31.

Molecular Formula	C₃₄H₃₉N₃O₃S
Molecular Weight	569.76

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CYP3A4-IN-3

Use of CYP3A4-IN-3

Names

CYP3A4-IN-3 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.