GATA4-IN-3
Modify Date: 2025-08-22 21:39:06
GATA4-IN-3 structure
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Common Name | GATA4-IN-3 | ||
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| CAS Number | 544681-96-1 | Molecular Weight | 349.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H23N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GATA4-IN-3GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression[1]. |
| Name | GATA4-NKX2-5-IN-1 |
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| Description | GATA4-NKX2-5-IN-1 (Compound 3) dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM. GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression[1]. |
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| Related Catalog | |
| Target |
IC50: 3 μM (GATA4–NKX2-5)[1] |
| References |
| Molecular Formula | C21H23N3O2 |
|---|---|
| Molecular Weight | 349.43 |
| InChIKey | UDDOZWWBHVIGDS-UHFFFAOYSA-N |
| SMILES | CCN(CC)c1ccc(NC(=O)c2c(-c3ccccc3)noc2C)cc1 |