Nampt-IN-3

Modify Date: 2024-01-15 02:58:48

Nampt-IN-3 structure	Common Name	Nampt-IN-3
	CAS Number	2121591-52-2	Molecular Weight	503.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₅N₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Nampt-IN-3

Nampt-IN-3 (Compound 35) simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death[1].

Name	Nampt-IN-3

Description	Nampt-IN-3 (Compound 35) simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Metabolic Enzyme/Protease >> Nampt Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Dong G, et al. Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. J Med Chem. 2017 Oct 12;60(19):7965-7983.

Molecular Formula	C₂₉H₂₅N₇O₂
Molecular Weight	503.55

Nampt-IN-3

Use of Nampt-IN-3

Names

Nampt-IN-3 Biological Activity

Chemical & Physical Properties