486449-65-4

486449-65-4 structure

Name: CD80-IN-3
Chemical Name: 4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid
CAS Number: 486449-65-4
Molecular Formula: C₁₇H₁₀FN₃O₃
Molecular Weight: 323.27800
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-03-01 02:14:28
Modify Date: 2025-08-25 08:44:14
CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.

Name	4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid

Description	CD80-IN-3, a potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11(12):1651-8.