DUBs-IN-3

Modify Date: 2025-08-27 11:13:30

DUBs-IN-3 Structure
DUBs-IN-3 structure
Common Name DUBs-IN-3
CAS Number 924296-17-3 Molecular Weight 287.27600
Density 1.31g/cm3 Boiling Point 560.4ºC at 760 mmHg
Molecular Formula C16H9N5O Melting Point N/A
MSDS N/A Flash Point 292.7ºC

 Use of DUBs-IN-3


DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.

 Names

Name 9-[(Allyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Synonym More Synonyms

 DUBs-IN-3 Biological Activity

Description DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.
Related Catalog
Target

IC50: 0.56 μM (USP8)[1]

References

[1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.

 Chemical & Physical Properties

Density 1.31g/cm3
Boiling Point 560.4ºC at 760 mmHg
Molecular Formula C16H9N5O
Molecular Weight 287.27600
Flash Point 292.7ºC
Exact Mass 287.08100
PSA 94.95000
LogP 2.15536
Index of Refraction 1.684

 Synonyms

DUBs-IN-3
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