924296-17-3

924296-17-3 structure

Name: DUBs-IN-3
Chemical Name: 9-[(Allyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
CAS Number: 924296-17-3
Molecular Formula: C₁₆H₉N₅O
Molecular Weight: 287.27600
Catalog: Signaling Pathways Cell Cycle/DNA Damage Deubiquitinase
Create Date: 2018-12-28 20:41:32
Modify Date: 2025-08-27 11:13:30
DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.

Name	9-[(Allyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Synonyms	DUBs-IN-3

Description	DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase Research Areas >> Cancer
Target	IC50: 0.56 μM (USP8)[1]
References	[1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.