Thalidomide-NH-PEG2-C2-NH2 TFA

Modify Date: 2024-01-09 22:14:31

Thalidomide-NH-PEG2-C2-NH2 TFA structure	Common Name	Thalidomide-NH-PEG2-C2-NH2 TFA
	CAS Number	2097509-36-7	Molecular Weight	518.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₅F₃N₄O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide-NH-PEG2-C2-NH2 TFA

Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

Name	Thalidomide-NH-PEG2-C2-NH2 TFA

Description	Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

Molecular Formula	C₂₁H₂₅F₃N₄O₈
Molecular Weight	518.44

Hazard Codes	Xi