Thalidomide-NH-PEG2-C2-NH-Boc

Modify Date: 2025-08-25 17:42:21

Thalidomide-NH-PEG2-C2-NH-Boc Structure
Thalidomide-NH-PEG2-C2-NH-Boc structure
Common Name Thalidomide-NH-PEG2-C2-NH-Boc
CAS Number 2097509-40-3 Molecular Weight 504.53
Density N/A Boiling Point N/A
Molecular Formula C24H32N4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-PEG2-C2-NH-Boc


Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology[1].

 Names

Name Thalidomide-NH-PEG2-C2-NH-Boc

 Thalidomide-NH-PEG2-C2-NH-Boc Biological Activity

Description Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology[1].
Related Catalog
In Vitro dBRD9 (0-1 μM) exerts a potent anti-proliferative effect, exceeding non-degrading probe potencies in excesses of 10 to 100 fold[1].
References

[1]. David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.

 Chemical & Physical Properties

Molecular Formula C24H32N4O8
Molecular Weight 504.53

 Safety Information

Hazard Codes Xi
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Thalidomide-NH-PEG2-C2-NH-Boc suppliers

Thalidomide-NH-PEG2-C2-NH-Boc price