2093386-36-6
2093386-36-6 structure
- Name: Thalidomide-NH-(CH2)3-NH-Boc
- Chemical Name: Thalidomide-NH-C3-NH-Boc
- CAS Number: 2093386-36-6
- Molecular Formula: C21H26N4O6
- Molecular Weight: 430.45
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2023-02-19 14:52:13
- Modify Date: 2025-08-27 11:32:04
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Thalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol.
| Name | Thalidomide-NH-C3-NH-Boc |
|---|
| Description | Thalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol. |
|---|---|
| Related Catalog |
| Molecular Formula | C21H26N4O6 |
|---|---|
| Molecular Weight | 430.45 |