eIF4A3-IN-2

Modify Date: 2024-01-10 07:10:16

eIF4A3-IN-2 structure	Common Name	eIF4A3-IN-2
	CAS Number	2095677-20-4	Molecular Weight	602.70
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₁₉Br₂ClN₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of eIF4A3-IN-2

eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM.

Name	eIF4A3-IN-2

Description	eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Eukaryotic Initiation Factor (eIF)
Target	IC50: 110 nM (eIF4A3)[1]
In Vitro	eIF4A3-IN-2 (compound 2) binds to the allosteric region in eIF4A3 and inhibits in vitro ATPase, helicase, and cellular nonsense-mediated RNA decay (NMD) activities[1].
References	[1]. Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017 Jul 21;12(7):1760-1768.

Molecular Formula	C₂₅H₁₉Br₂ClN₄O₂
Molecular Weight	602.70
Storage condition	2-8℃

DC Chemicals Limited
China
Product Name: eIF4A3-IN-2
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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