eIF4A3-IN-2

Modify Date: 2025-09-01 18:47:09

eIF4A3-IN-2 Structure
eIF4A3-IN-2 structure
 Common Name eIF4A3-IN-2
CAS Number 2095677-20-4 Molecular Weight 602.70
Density N/A Boiling Point N/A
Molecular Formula C25H19Br2ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of eIF4A3-IN-2


eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM.

 Names

Name eIF4A3-IN-2

 eIF4A3-IN-2 Biological Activity

Description eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM.
Related Catalog
Target

IC50: 110 nM (eIF4A3)[1]

In Vitro eIF4A3-IN-2 (compound 2) binds to the allosteric region in eIF4A3 and inhibits in vitro ATPase, helicase, and cellular nonsense-mediated RNA decay (NMD) activities[1].
References

[1]. Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017 Jul 21;12(7):1760-1768.

 Chemical & Physical Properties

Molecular Formula C25H19Br2ClN4O2
Molecular Weight 602.70
Storage condition 2-8℃
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Chemsrc provides eIF4A3-IN-2(CAS#:2095677-20-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of eIF4A3-IN-2 are included as well.>> amp version: eIF4A3-IN-2

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