(R)-eIF4A3-IN-2

Modify Date: 2024-01-16 23:16:33

(R)-eIF4A3-IN-2 Structure
(R)-eIF4A3-IN-2 structure
Common Name (R)-eIF4A3-IN-2
CAS Number 2095484-82-3 Molecular Weight 602.70
Density N/A Boiling Point N/A
Molecular Formula C25H19Br2ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-eIF4A3-IN-2


(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].

 Names

Name (R)-eIF4A3-IN-2

 (R)-eIF4A3-IN-2 Biological Activity

Description (R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].
Related Catalog
In Vitro Eukaryotic initiation factor 4A-3 (eIF4A3) is an Asp-Glu-Ala-Asp (DEAD) box-family adenosine triphosphate (ATP)-dependent RNA helicase[1].
References

[1]. Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017;12(7):1760-1768.

 Chemical & Physical Properties

Molecular Formula C25H19Br2ClN4O2
Molecular Weight 602.70