1402931-66-1

1402931-66-1 structure
1402931-66-1 structure
  • Name: eIF4A3-IN-15
  • Chemical Name: eIF4A3-IN-15
  • CAS Number: 1402931-66-1
  • Molecular Formula: C28H29NO7
  • Molecular Weight: 491.53
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Eukaryotic Initiation Factor (eIF)
  • Create Date: 2023-05-12 18:43:48
  • Modify Date: 2024-04-06 10:51:57
  • eIF4A3-IN-15 (compound 52) is a silvestrol (HY-13251) analogue. eIF4A3-IN-15 interferes the assembling of eIF4F translation complex with EC50s of 11, 700 and 120 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-15 can be used for the research of human cancer pathogenesis[1].

Name eIF4A3-IN-15
Description eIF4A3-IN-15 (compound 52) is a silvestrol (HY-13251) analogue. eIF4A3-IN-15 interferes the assembling of eIF4F translation complex with EC50s of 11, 700 and 120 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-15 can be used for the research of human cancer pathogenesis[1].
Related Catalog
References

[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.  

Molecular Formula C28H29NO7
Molecular Weight 491.53